WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:T cell activation       ID:GO:0042110
C=336; O=27; E=1.86; R=14.51; rawP=1.49e-24; adjP=1.29e-21
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000237541 NA HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3118 ENSG00000237541
2  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
3  ENSG00000117091 NA CD48 CD48 molecule 962 ENSG00000117091
4  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
5  ENSG00000198286 NA CARD11 caspase recruitment domain family, member 11 84433 ENSG00000198286
6  ENSG00000182866 NA LCK lymphocyte-specific protein tyrosine kinase 3932 ENSG00000182866
7  ENSG00000181847 NA TIGIT T cell immunoreceptor with Ig and ITIM domains 201633 ENSG00000181847
8  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
9  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
10  ENSG00000100351 NA GRAP2 GRB2-related adaptor protein 2 9402 ENSG00000100351
11  ENSG00000152495 NA CAMK4 calcium/calmodulin-dependent protein kinase IV 814 ENSG00000152495
12  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
13  ENSG00000196684 NA HSH2D hematopoietic SH2 domain containing 84941 ENSG00000196684
14  ENSG00000134242 NA PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 26191 ENSG00000134242
15  ENSG00000161570 NA CCL5 chemokine (C-C motif) ligand 5 6352 ENSG00000161570
16  ENSG00000168421 NA RHOH ras homolog family member H 399 ENSG00000168421
17  ENSG00000173762 NA CD7 CD7 molecule 924 ENSG00000173762
18  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
19  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
20  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
21  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
22  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
23  ENSG00000115085 NA ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 ENSG00000115085
24  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
25  ENSG00000232629 NA HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 3120 ENSG00000232629
26  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286
27  ENSG00000113263 NA ITK IL2-inducible T-cell kinase 3702 ENSG00000113263


Database:biological process       Name:immune response       ID:GO:0006955
C=1071; O=39; E=5.93; R=6.58; rawP=2.74e-23; adjP=8.39e-21
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198286 NA CARD11 caspase recruitment domain family, member 11 84433 ENSG00000198286
2  ENSG00000164764 NA SBSPON somatomedin B and thrombospondin, type 1 domain containing 157869 ENSG00000164764
3  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
4  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
5  ENSG00000100351 NA GRAP2 GRB2-related adaptor protein 2 9402 ENSG00000100351
6  ENSG00000152495 NA CAMK4 calcium/calmodulin-dependent protein kinase IV 814 ENSG00000152495
7  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
8  ENSG00000161570 NA CCL5 chemokine (C-C motif) ligand 5 6352 ENSG00000161570
9  ENSG00000173762 NA CD7 CD7 molecule 924 ENSG00000173762
10  ENSG00000213903 NA LTB4R leukotriene B4 receptor 1241 ENSG00000213903
11  ENSG00000154451 NA GBP5 guanylate binding protein 5 115362 ENSG00000154451
12  ENSG00000153283 NA CD96 CD96 molecule 10225 ENSG00000153283
13  ENSG00000183918 NA SH2D1A SH2 domain containing 1A 4068 ENSG00000183918
14  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
15  ENSG00000129277 NA CCL4 chemokine (C-C motif) ligand 4 6351 ENSG00000129277
16  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286
17  ENSG00000006075 NA CCL3 chemokine (C-C motif) ligand 3 6348 ENSG00000006075
18  ENSG00000124256 NA ZBP1 Z-DNA binding protein 1 81030 ENSG00000124256
19  ENSG00000180644 NA PRF1 perforin 1 (pore forming protein) 5551 ENSG00000180644
20  ENSG00000172543 NA CTSW cathepsin W 1521 ENSG00000172543
21  ENSG00000113263 NA ITK IL2-inducible T-cell kinase 3702 ENSG00000113263
22  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
23  ENSG00000139626 NA ITGB7 integrin, beta 7 3695 ENSG00000139626
24  ENSG00000237541 NA HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3118 ENSG00000237541
25  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
26  ENSG00000145649 NA GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 3001 ENSG00000145649
27  ENSG00000197540 NA GZMM granzyme M (lymphocyte met-ase 1) 3004 ENSG00000197540
28  ENSG00000182866 NA LCK lymphocyte-specific protein tyrosine kinase 3932 ENSG00000182866
29  ENSG00000147168 NA IL2RG interleukin 2 receptor, gamma 3561 ENSG00000147168
30  ENSG00000134242 NA PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 26191 ENSG00000134242
31  ENSG00000141293 NA SKAP1 src kinase associated phosphoprotein 1 8631 ENSG00000141293
32  ENSG00000166086 NA JAM3 junctional adhesion molecule 3 83700 ENSG00000166086
33  ENSG00000156738 NA MS4A1 membrane-spanning 4-domains, subfamily A, member 1 931 ENSG00000156738
34  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
35  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
36  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
37  ENSG00000115085 NA ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 ENSG00000115085
38  ENSG00000232629 NA HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 3120 ENSG00000232629
39  ENSG00000160791 NA CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 ENSG00000160791


Database:biological process       Name:lymphocyte activation       ID:GO:0046649
C=466; O=29; E=2.58; R=11.24; rawP=2.91e-23; adjP=8.39e-21
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000237541 NA HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3118 ENSG00000237541
2  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
3  ENSG00000117091 NA CD48 CD48 molecule 962 ENSG00000117091
4  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
5  ENSG00000198286 NA CARD11 caspase recruitment domain family, member 11 84433 ENSG00000198286
6  ENSG00000182866 NA LCK lymphocyte-specific protein tyrosine kinase 3932 ENSG00000182866
7  ENSG00000181847 NA TIGIT T cell immunoreceptor with Ig and ITIM domains 201633 ENSG00000181847
8  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
9  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
10  ENSG00000100351 NA GRAP2 GRB2-related adaptor protein 2 9402 ENSG00000100351
11  ENSG00000152495 NA CAMK4 calcium/calmodulin-dependent protein kinase IV 814 ENSG00000152495
12  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
13  ENSG00000196684 NA HSH2D hematopoietic SH2 domain containing 84941 ENSG00000196684
14  ENSG00000057657 NA PRDM1 PR domain containing 1, with ZNF domain 639 ENSG00000057657
15  ENSG00000134242 NA PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 26191 ENSG00000134242
16  ENSG00000161570 NA CCL5 chemokine (C-C motif) ligand 5 6352 ENSG00000161570
17  ENSG00000168421 NA RHOH ras homolog family member H 399 ENSG00000168421
18  ENSG00000173762 NA CD7 CD7 molecule 924 ENSG00000173762
19  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
20  ENSG00000156738 NA MS4A1 membrane-spanning 4-domains, subfamily A, member 1 931 ENSG00000156738
21  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
22  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
23  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
24  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
25  ENSG00000115085 NA ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 ENSG00000115085
26  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
27  ENSG00000232629 NA HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 3120 ENSG00000232629
28  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286
29  ENSG00000113263 NA ITK IL2-inducible T-cell kinase 3702 ENSG00000113263


Database:biological process       Name:immune system process       ID:GO:0002376
C=1792; O=47; E=9.92; R=4.74; rawP=8.88e-23; adjP=1.92e-20
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198286 NA CARD11 caspase recruitment domain family, member 11 84433 ENSG00000198286
2  ENSG00000164764 NA SBSPON somatomedin B and thrombospondin, type 1 domain containing 157869 ENSG00000164764
3  ENSG00000181847 NA TIGIT T cell immunoreceptor with Ig and ITIM domains 201633 ENSG00000181847
4  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
5  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
6  ENSG00000100351 NA GRAP2 GRB2-related adaptor protein 2 9402 ENSG00000100351
7  ENSG00000152495 NA CAMK4 calcium/calmodulin-dependent protein kinase IV 814 ENSG00000152495
8  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
9  ENSG00000161570 NA CCL5 chemokine (C-C motif) ligand 5 6352 ENSG00000161570
10  ENSG00000173762 NA CD7 CD7 molecule 924 ENSG00000173762
11  ENSG00000213903 NA LTB4R leukotriene B4 receptor 1241 ENSG00000213903
12  ENSG00000154451 NA GBP5 guanylate binding protein 5 115362 ENSG00000154451
13  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
14  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
15  ENSG00000153283 NA CD96 CD96 molecule 10225 ENSG00000153283
16  ENSG00000183918 NA SH2D1A SH2 domain containing 1A 4068 ENSG00000183918
17  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
18  ENSG00000129277 NA CCL4 chemokine (C-C motif) ligand 4 6351 ENSG00000129277
19  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286
20  ENSG00000006075 NA CCL3 chemokine (C-C motif) ligand 3 6348 ENSG00000006075
21  ENSG00000124256 NA ZBP1 Z-DNA binding protein 1 81030 ENSG00000124256
22  ENSG00000180644 NA PRF1 perforin 1 (pore forming protein) 5551 ENSG00000180644
23  ENSG00000172543 NA CTSW cathepsin W 1521 ENSG00000172543
24  ENSG00000113263 NA ITK IL2-inducible T-cell kinase 3702 ENSG00000113263
25  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
26  ENSG00000139626 NA ITGB7 integrin, beta 7 3695 ENSG00000139626
27  ENSG00000237541 NA HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3118 ENSG00000237541
28  ENSG00000117091 NA CD48 CD48 molecule 962 ENSG00000117091
29  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
30  ENSG00000197540 NA GZMM granzyme M (lymphocyte met-ase 1) 3004 ENSG00000197540
31  ENSG00000145649 NA GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 3001 ENSG00000145649
32  ENSG00000182866 NA LCK lymphocyte-specific protein tyrosine kinase 3932 ENSG00000182866
33  ENSG00000147168 NA IL2RG interleukin 2 receptor, gamma 3561 ENSG00000147168
34  ENSG00000196684 NA HSH2D hematopoietic SH2 domain containing 84941 ENSG00000196684
35  ENSG00000057657 NA PRDM1 PR domain containing 1, with ZNF domain 639 ENSG00000057657
36  ENSG00000134242 NA PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 26191 ENSG00000134242
37  ENSG00000168421 NA RHOH ras homolog family member H 399 ENSG00000168421
38  ENSG00000141293 NA SKAP1 src kinase associated phosphoprotein 1 8631 ENSG00000141293
39  ENSG00000166086 NA JAM3 junctional adhesion molecule 3 83700 ENSG00000166086
40  ENSG00000156738 NA MS4A1 membrane-spanning 4-domains, subfamily A, member 1 931 ENSG00000156738
41  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
42  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
43  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
44  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
45  ENSG00000115085 NA ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 ENSG00000115085
46  ENSG00000232629 NA HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 3120 ENSG00000232629
47  ENSG00000160791 NA CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 ENSG00000160791


Database:biological process       Name:leukocyte activation       ID:GO:0045321
C=552; O=30; E=3.06; R=9.82; rawP=2.16e-22; adjP=3.74e-20
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000237541 NA HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3118 ENSG00000237541
2  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
3  ENSG00000117091 NA CD48 CD48 molecule 962 ENSG00000117091
4  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
5  ENSG00000198286 NA CARD11 caspase recruitment domain family, member 11 84433 ENSG00000198286
6  ENSG00000182866 NA LCK lymphocyte-specific protein tyrosine kinase 3932 ENSG00000182866
7  ENSG00000181847 NA TIGIT T cell immunoreceptor with Ig and ITIM domains 201633 ENSG00000181847
8  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
9  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
10  ENSG00000100351 NA GRAP2 GRB2-related adaptor protein 2 9402 ENSG00000100351
11  ENSG00000152495 NA CAMK4 calcium/calmodulin-dependent protein kinase IV 814 ENSG00000152495
12  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
13  ENSG00000196684 NA HSH2D hematopoietic SH2 domain containing 84941 ENSG00000196684
14  ENSG00000057657 NA PRDM1 PR domain containing 1, with ZNF domain 639 ENSG00000057657
15  ENSG00000134242 NA PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 26191 ENSG00000134242
16  ENSG00000161570 NA CCL5 chemokine (C-C motif) ligand 5 6352 ENSG00000161570
17  ENSG00000168421 NA RHOH ras homolog family member H 399 ENSG00000168421
18  ENSG00000173762 NA CD7 CD7 molecule 924 ENSG00000173762
19  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
20  ENSG00000156738 NA MS4A1 membrane-spanning 4-domains, subfamily A, member 1 931 ENSG00000156738
21  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
22  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
23  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
24  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
25  ENSG00000115085 NA ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 ENSG00000115085
26  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
27  ENSG00000232629 NA HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 3120 ENSG00000232629
28  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286
29  ENSG00000006075 NA CCL3 chemokine (C-C motif) ligand 3 6348 ENSG00000006075
30  ENSG00000113263 NA ITK IL2-inducible T-cell kinase 3702 ENSG00000113263


Database:biological process       Name:cell activation       ID:GO:0001775
C=755; O=32; E=4.18; R=7.66; rawP=1.10e-20; adjP=1.59e-18
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198286 NA CARD11 caspase recruitment domain family, member 11 84433 ENSG00000198286
2  ENSG00000181847 NA TIGIT T cell immunoreceptor with Ig and ITIM domains 201633 ENSG00000181847
3  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
4  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
5  ENSG00000130956 NA HABP4 hyaluronan binding protein 4 22927 ENSG00000130956
6  ENSG00000100351 NA GRAP2 GRB2-related adaptor protein 2 9402 ENSG00000100351
7  ENSG00000152495 NA CAMK4 calcium/calmodulin-dependent protein kinase IV 814 ENSG00000152495
8  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
9  ENSG00000161570 NA CCL5 chemokine (C-C motif) ligand 5 6352 ENSG00000161570
10  ENSG00000173762 NA CD7 CD7 molecule 924 ENSG00000173762
11  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
12  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
13  ENSG00000128340 NA RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 5880 ENSG00000128340
14  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
15  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286
16  ENSG00000006075 NA CCL3 chemokine (C-C motif) ligand 3 6348 ENSG00000006075
17  ENSG00000113263 NA ITK IL2-inducible T-cell kinase 3702 ENSG00000113263
18  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
19  ENSG00000237541 NA HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3118 ENSG00000237541
20  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
21  ENSG00000117091 NA CD48 CD48 molecule 962 ENSG00000117091
22  ENSG00000182866 NA LCK lymphocyte-specific protein tyrosine kinase 3932 ENSG00000182866
23  ENSG00000196684 NA HSH2D hematopoietic SH2 domain containing 84941 ENSG00000196684
24  ENSG00000134242 NA PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 26191 ENSG00000134242
25  ENSG00000057657 NA PRDM1 PR domain containing 1, with ZNF domain 639 ENSG00000057657
26  ENSG00000168421 NA RHOH ras homolog family member H 399 ENSG00000168421
27  ENSG00000156738 NA MS4A1 membrane-spanning 4-domains, subfamily A, member 1 931 ENSG00000156738
28  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
29  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
30  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
31  ENSG00000232629 NA HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 3120 ENSG00000232629
32  ENSG00000115085 NA ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 ENSG00000115085


Database:biological process       Name:regulation of immune system process       ID:GO:0002682
C=865; O=31; E=4.79; R=6.47; rawP=6.78e-18; adjP=8.38e-16
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000237541 NA HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3118 ENSG00000237541
2  ENSG00000139626 NA ITGB7 integrin, beta 7 3695 ENSG00000139626
3  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
4  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
5  ENSG00000198286 NA CARD11 caspase recruitment domain family, member 11 84433 ENSG00000198286
6  ENSG00000182866 NA LCK lymphocyte-specific protein tyrosine kinase 3932 ENSG00000182866
7  ENSG00000181847 NA TIGIT T cell immunoreceptor with Ig and ITIM domains 201633 ENSG00000181847
8  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
9  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
10  ENSG00000100351 NA GRAP2 GRB2-related adaptor protein 2 9402 ENSG00000100351
11  ENSG00000152495 NA CAMK4 calcium/calmodulin-dependent protein kinase IV 814 ENSG00000152495
12  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
13  ENSG00000057657 NA PRDM1 PR domain containing 1, with ZNF domain 639 ENSG00000057657
14  ENSG00000134242 NA PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 26191 ENSG00000134242
15  ENSG00000161570 NA CCL5 chemokine (C-C motif) ligand 5 6352 ENSG00000161570
16  ENSG00000141293 NA SKAP1 src kinase associated phosphoprotein 1 8631 ENSG00000141293
17  ENSG00000166086 NA JAM3 junctional adhesion molecule 3 83700 ENSG00000166086
18  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
19  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
20  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
21  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
22  ENSG00000153283 NA CD96 CD96 molecule 10225 ENSG00000153283
23  ENSG00000183918 NA SH2D1A SH2 domain containing 1A 4068 ENSG00000183918
24  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
25  ENSG00000115085 NA ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 ENSG00000115085
26  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
27  ENSG00000232629 NA HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 3120 ENSG00000232629
28  ENSG00000129277 NA CCL4 chemokine (C-C motif) ligand 4 6351 ENSG00000129277
29  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286
30  ENSG00000006075 NA CCL3 chemokine (C-C motif) ligand 3 6348 ENSG00000006075
31  ENSG00000113263 NA ITK IL2-inducible T-cell kinase 3702 ENSG00000113263


Database:biological process       Name:regulation of T cell activation       ID:GO:0050863
C=223; O=19; E=1.23; R=15.39; rawP=9.14e-18; adjP=9.88e-16
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000237541 NA HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3118 ENSG00000237541
2  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
3  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
4  ENSG00000198286 NA CARD11 caspase recruitment domain family, member 11 84433 ENSG00000198286
5  ENSG00000182866 NA LCK lymphocyte-specific protein tyrosine kinase 3932 ENSG00000182866
6  ENSG00000181847 NA TIGIT T cell immunoreceptor with Ig and ITIM domains 201633 ENSG00000181847
7  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
8  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
9  ENSG00000100351 NA GRAP2 GRB2-related adaptor protein 2 9402 ENSG00000100351
10  ENSG00000152495 NA CAMK4 calcium/calmodulin-dependent protein kinase IV 814 ENSG00000152495
11  ENSG00000134242 NA PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 26191 ENSG00000134242
12  ENSG00000161570 NA CCL5 chemokine (C-C motif) ligand 5 6352 ENSG00000161570
13  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
14  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
15  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
16  ENSG00000115085 NA ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 ENSG00000115085
17  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
18  ENSG00000232629 NA HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 3120 ENSG00000232629
19  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286


Database:biological process       Name:regulation of lymphocyte activation       ID:GO:0051249
C=290; O=20; E=1.61; R=12.46; rawP=7.22e-17; adjP=6.94e-15
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000237541 NA HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3118 ENSG00000237541
2  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
3  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
4  ENSG00000198286 NA CARD11 caspase recruitment domain family, member 11 84433 ENSG00000198286
5  ENSG00000182866 NA LCK lymphocyte-specific protein tyrosine kinase 3932 ENSG00000182866
6  ENSG00000181847 NA TIGIT T cell immunoreceptor with Ig and ITIM domains 201633 ENSG00000181847
7  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
8  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
9  ENSG00000100351 NA GRAP2 GRB2-related adaptor protein 2 9402 ENSG00000100351
10  ENSG00000152495 NA CAMK4 calcium/calmodulin-dependent protein kinase IV 814 ENSG00000152495
11  ENSG00000057657 NA PRDM1 PR domain containing 1, with ZNF domain 639 ENSG00000057657
12  ENSG00000134242 NA PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 26191 ENSG00000134242
13  ENSG00000161570 NA CCL5 chemokine (C-C motif) ligand 5 6352 ENSG00000161570
14  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
15  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
16  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
17  ENSG00000115085 NA ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 ENSG00000115085
18  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
19  ENSG00000232629 NA HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 3120 ENSG00000232629
20  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286


Database:biological process       Name:regulation of leukocyte activation       ID:GO:0002694
C=330; O=20; E=1.83; R=10.95; rawP=8.84e-16; adjP=7.65e-14
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000237541 NA HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3118 ENSG00000237541
2  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
3  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
4  ENSG00000198286 NA CARD11 caspase recruitment domain family, member 11 84433 ENSG00000198286
5  ENSG00000182866 NA LCK lymphocyte-specific protein tyrosine kinase 3932 ENSG00000182866
6  ENSG00000181847 NA TIGIT T cell immunoreceptor with Ig and ITIM domains 201633 ENSG00000181847
7  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
8  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
9  ENSG00000100351 NA GRAP2 GRB2-related adaptor protein 2 9402 ENSG00000100351
10  ENSG00000152495 NA CAMK4 calcium/calmodulin-dependent protein kinase IV 814 ENSG00000152495
11  ENSG00000057657 NA PRDM1 PR domain containing 1, with ZNF domain 639 ENSG00000057657
12  ENSG00000134242 NA PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 26191 ENSG00000134242
13  ENSG00000161570 NA CCL5 chemokine (C-C motif) ligand 5 6352 ENSG00000161570
14  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
15  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
16  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
17  ENSG00000115085 NA ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 ENSG00000115085
18  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
19  ENSG00000232629 NA HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 3120 ENSG00000232629
20  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286


Database:molecular function       Name:receptor activity       ID:GO:0004872
C=1531; O=27; E=8.41; R=3.21; rawP=2.19e-08; adjP=3.31e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000139626 NA ITGB7 integrin, beta 7 3695 ENSG00000139626
2  ENSG00000117091 NA CD48 CD48 molecule 962 ENSG00000117091
3  ENSG00000164764 NA SBSPON somatomedin B and thrombospondin, type 1 domain containing 157869 ENSG00000164764
4  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
5  ENSG00000147168 NA IL2RG interleukin 2 receptor, gamma 3561 ENSG00000147168
6  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
7  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
8  ENSG00000100385 NA IL2RB interleukin 2 receptor, beta 3560 ENSG00000100385
9  ENSG00000172215 NA CXCR6 chemokine (C-X-C motif) receptor 6 10663 ENSG00000172215
10  ENSG00000173762 NA CD7 CD7 molecule 924 ENSG00000173762
11  ENSG00000213903 NA LTB4R leukotriene B4 receptor 1241 ENSG00000213903
12  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
13  ENSG00000111796 NA KLRB1 killer cell lectin-like receptor subfamily B, member 1 3820 ENSG00000111796
14  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
15  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
16  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
17  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
18  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
19  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
20  ENSG00000110848 NA CD69 CD69 molecule 969 ENSG00000110848
21  ENSG00000013725 NA CD6 CD6 molecule 923 ENSG00000013725
22  ENSG00000164120 NA HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 3248 ENSG00000164120
23  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286
24  ENSG00000162739 NA SLAMF6 SLAM family member 6 114836 ENSG00000162739
25  ENSG00000174946 NA GPR171 G protein-coupled receptor 171 29909 ENSG00000174946
26  ENSG00000148053 NA NTRK2 neurotrophic tyrosine kinase, receptor, type 2 4915 ENSG00000148053
27  ENSG00000160791 NA CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 ENSG00000160791


Database:molecular function       Name:coreceptor activity       ID:GO:0015026
C=23; O=5; E=0.13; R=39.55; rawP=1.38e-07; adjP=1.04e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
2  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
3  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
4  ENSG00000172215 NA CXCR6 chemokine (C-X-C motif) receptor 6 10663 ENSG00000172215
5  ENSG00000160791 NA CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 ENSG00000160791


Database:molecular function       Name:CCR5 chemokine receptor binding       ID:GO:0031730
C=5; O=3; E=0.03; R=109.17; rawP=1.59e-06; adjP=8.00e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000006075 NA CCL3 chemokine (C-C motif) ligand 3 6348 ENSG00000006075
2  ENSG00000161570 NA CCL5 chemokine (C-C motif) ligand 5 6352 ENSG00000161570
3  ENSG00000129277 NA CCL4 chemokine (C-C motif) ligand 4 6351 ENSG00000129277


Database:molecular function       Name:CCR1 chemokine receptor binding       ID:GO:0031726
C=6; O=3; E=0.03; R=90.98; rawP=3.17e-06; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000006075 NA CCL3 chemokine (C-C motif) ligand 3 6348 ENSG00000006075
2  ENSG00000161570 NA CCL5 chemokine (C-C motif) ligand 5 6352 ENSG00000161570
3  ENSG00000129277 NA CCL4 chemokine (C-C motif) ligand 4 6351 ENSG00000129277


Database:molecular function       Name:cytokine receptor activity       ID:GO:0004896
C=81; O=6; E=0.45; R=13.48; rawP=5.37e-06; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
2  ENSG00000100385 NA IL2RB interleukin 2 receptor, beta 3560 ENSG00000100385
3  ENSG00000172215 NA CXCR6 chemokine (C-X-C motif) receptor 6 10663 ENSG00000172215
4  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
5  ENSG00000160791 NA CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 ENSG00000160791
6  ENSG00000147168 NA IL2RG interleukin 2 receptor, gamma 3561 ENSG00000147168


Database:molecular function       Name:interleukin-7 receptor activity       ID:GO:0004917
C=2; O=2; E=0.01; R=181.95; rawP=2.98e-05; adjP=0.0006
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
2  ENSG00000147168 NA IL2RG interleukin 2 receptor, gamma 3561 ENSG00000147168


Database:molecular function       Name:signaling receptor activity       ID:GO:0038023
C=1325; O=20; E=7.28; R=2.75; rawP=2.43e-05; adjP=0.0006
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
2  ENSG00000147168 NA IL2RG interleukin 2 receptor, gamma 3561 ENSG00000147168
3  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
4  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
5  ENSG00000100385 NA IL2RB interleukin 2 receptor, beta 3560 ENSG00000100385
6  ENSG00000172215 NA CXCR6 chemokine (C-X-C motif) receptor 6 10663 ENSG00000172215
7  ENSG00000213903 NA LTB4R leukotriene B4 receptor 1241 ENSG00000213903
8  ENSG00000111796 NA KLRB1 killer cell lectin-like receptor subfamily B, member 1 3820 ENSG00000111796
9  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
10  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
11  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
12  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
13  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
14  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
15  ENSG00000110848 NA CD69 CD69 molecule 969 ENSG00000110848
16  ENSG00000164120 NA HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 3248 ENSG00000164120
17  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286
18  ENSG00000174946 NA GPR171 G protein-coupled receptor 171 29909 ENSG00000174946
19  ENSG00000148053 NA NTRK2 neurotrophic tyrosine kinase, receptor, type 2 4915 ENSG00000148053
20  ENSG00000160791 NA CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 ENSG00000160791


Database:molecular function       Name:interleukin-2 binding       ID:GO:0019976
C=3; O=2; E=0.02; R=121.30; rawP=8.92e-05; adjP=0.0011
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100385 NA IL2RB interleukin 2 receptor, beta 3560 ENSG00000100385
2  ENSG00000147168 NA IL2RG interleukin 2 receptor, gamma 3561 ENSG00000147168


Database:molecular function       Name:molecular transducer activity       ID:GO:0060089
C=1628; O=21; E=8.95; R=2.35; rawP=0.0001; adjP=0.0011
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
2  ENSG00000147168 NA IL2RG interleukin 2 receptor, gamma 3561 ENSG00000147168
3  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
4  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
5  ENSG00000100385 NA IL2RB interleukin 2 receptor, beta 3560 ENSG00000100385
6  ENSG00000172215 NA CXCR6 chemokine (C-X-C motif) receptor 6 10663 ENSG00000172215
7  ENSG00000213903 NA LTB4R leukotriene B4 receptor 1241 ENSG00000213903
8  ENSG00000111796 NA KLRB1 killer cell lectin-like receptor subfamily B, member 1 3820 ENSG00000111796
9  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
10  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
11  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
12  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
13  ENSG00000104814 NA MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 11184 ENSG00000104814
14  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
15  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
16  ENSG00000110848 NA CD69 CD69 molecule 969 ENSG00000110848
17  ENSG00000164120 NA HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 3248 ENSG00000164120
18  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286
19  ENSG00000174946 NA GPR171 G protein-coupled receptor 171 29909 ENSG00000174946
20  ENSG00000148053 NA NTRK2 neurotrophic tyrosine kinase, receptor, type 2 4915 ENSG00000148053
21  ENSG00000160791 NA CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 ENSG00000160791


Database:molecular function       Name:signal transducer activity       ID:GO:0004871
C=1628; O=21; E=8.95; R=2.35; rawP=0.0001; adjP=0.0011
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
2  ENSG00000147168 NA IL2RG interleukin 2 receptor, gamma 3561 ENSG00000147168
3  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
4  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
5  ENSG00000100385 NA IL2RB interleukin 2 receptor, beta 3560 ENSG00000100385
6  ENSG00000172215 NA CXCR6 chemokine (C-X-C motif) receptor 6 10663 ENSG00000172215
7  ENSG00000213903 NA LTB4R leukotriene B4 receptor 1241 ENSG00000213903
8  ENSG00000111796 NA KLRB1 killer cell lectin-like receptor subfamily B, member 1 3820 ENSG00000111796
9  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
10  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
11  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
12  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
13  ENSG00000104814 NA MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 11184 ENSG00000104814
14  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
15  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
16  ENSG00000110848 NA CD69 CD69 molecule 969 ENSG00000110848
17  ENSG00000164120 NA HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 3248 ENSG00000164120
18  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286
19  ENSG00000174946 NA GPR171 G protein-coupled receptor 171 29909 ENSG00000174946
20  ENSG00000148053 NA NTRK2 neurotrophic tyrosine kinase, receptor, type 2 4915 ENSG00000148053
21  ENSG00000160791 NA CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 ENSG00000160791


Database:cellular component       Name:plasma membrane part       ID:GO:0044459
C=1918; O=41; E=9.90; R=4.14; rawP=8.57e-17; adjP=9.77e-15
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000198286 NA CARD11 caspase recruitment domain family, member 11 84433 ENSG00000198286
2  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
3  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
4  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
5  ENSG00000172215 NA CXCR6 chemokine (C-X-C motif) receptor 6 10663 ENSG00000172215
6  ENSG00000117600 NA LPPR4 lipid phosphate phosphatase-related protein type 4 9890 ENSG00000117600
7  ENSG00000100453 NA GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 3002 ENSG00000100453
8  ENSG00000213903 NA LTB4R leukotriene B4 receptor 1241 ENSG00000213903
9  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
10  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
11  ENSG00000153283 NA CD96 CD96 molecule 10225 ENSG00000153283
12  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
13  ENSG00000013725 NA CD6 CD6 molecule 923 ENSG00000013725
14  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286
15  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
16  ENSG00000139626 NA ITGB7 integrin, beta 7 3695 ENSG00000139626
17  ENSG00000237541 NA HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3118 ENSG00000237541
18  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
19  ENSG00000117091 NA CD48 CD48 molecule 962 ENSG00000117091
20  ENSG00000145649 NA GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 3001 ENSG00000145649
21  ENSG00000182866 NA LCK lymphocyte-specific protein tyrosine kinase 3932 ENSG00000182866
22  ENSG00000147168 NA IL2RG interleukin 2 receptor, gamma 3561 ENSG00000147168
23  ENSG00000105122 NA RASAL3 RAS protein activator like 3 64926 ENSG00000105122
24  ENSG00000134242 NA PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 26191 ENSG00000134242
25  ENSG00000181036 NA FCRL6 Fc receptor-like 6 343413 ENSG00000181036
26  ENSG00000142765 NA SYTL1 synaptotagmin-like 1 84958 ENSG00000142765
27  ENSG00000100385 NA IL2RB interleukin 2 receptor, beta 3560 ENSG00000100385
28  ENSG00000168421 NA RHOH ras homolog family member H 399 ENSG00000168421
29  ENSG00000156738 NA MS4A1 membrane-spanning 4-domains, subfamily A, member 1 931 ENSG00000156738
30  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
31  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
32  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
33  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
34  ENSG00000115085 NA ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 ENSG00000115085
35  ENSG00000110848 NA CD69 CD69 molecule 969 ENSG00000110848
36  ENSG00000232629 NA HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 3120 ENSG00000232629
37  ENSG00000105374 NA NKG7 natural killer cell group 7 sequence 4818 ENSG00000105374
38  ENSG00000143851 NA PTPN7 protein tyrosine phosphatase, non-receptor type 7 5778 ENSG00000143851
39  ENSG00000186854 NA TRABD2A TraB domain containing 2A 129293 ENSG00000186854
40  ENSG00000148053 NA NTRK2 neurotrophic tyrosine kinase, receptor, type 2 4915 ENSG00000148053
41  ENSG00000160791 NA CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 ENSG00000160791


Database:cellular component       Name:T cell receptor complex       ID:GO:0042101
C=12; O=8; E=0.06; R=129.19; rawP=1.77e-16; adjP=1.01e-14
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
2  ENSG00000198286 NA CARD11 caspase recruitment domain family, member 11 84433 ENSG00000198286
3  ENSG00000115085 NA ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 ENSG00000115085
4  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
5  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
6  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
7  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
8  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286


Database:cellular component       Name:external side of plasma membrane       ID:GO:0009897
C=203; O=17; E=1.05; R=16.23; rawP=2.88e-16; adjP=1.09e-14
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
2  ENSG00000117091 NA CD48 CD48 molecule 962 ENSG00000117091
3  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
4  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
5  ENSG00000147168 NA IL2RG interleukin 2 receptor, gamma 3561 ENSG00000147168
6  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
7  ENSG00000100385 NA IL2RB interleukin 2 receptor, beta 3560 ENSG00000100385
8  ENSG00000181036 NA FCRL6 Fc receptor-like 6 343413 ENSG00000181036
9  ENSG00000117600 NA LPPR4 lipid phosphate phosphatase-related protein type 4 9890 ENSG00000117600
10  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
11  ENSG00000156738 NA MS4A1 membrane-spanning 4-domains, subfamily A, member 1 931 ENSG00000156738
12  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
13  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
14  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
15  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
16  ENSG00000110848 NA CD69 CD69 molecule 969 ENSG00000110848
17  ENSG00000160791 NA CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 ENSG00000160791


Database:cellular component       Name:cell surface       ID:GO:0009986
C=495; O=21; E=2.55; R=8.22; rawP=5.65e-14; adjP=1.61e-12
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000131471 NA AOC3 amine oxidase, copper containing 3 (vascular adhesion protein 1) 8639 ENSG00000131471
2  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
3  ENSG00000117091 NA CD48 CD48 molecule 962 ENSG00000117091
4  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
5  ENSG00000181847 NA TIGIT T cell immunoreceptor with Ig and ITIM domains 201633 ENSG00000181847
6  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
7  ENSG00000147168 NA IL2RG interleukin 2 receptor, gamma 3561 ENSG00000147168
8  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
9  ENSG00000100385 NA IL2RB interleukin 2 receptor, beta 3560 ENSG00000100385
10  ENSG00000117600 NA LPPR4 lipid phosphate phosphatase-related protein type 4 9890 ENSG00000117600
11  ENSG00000181036 NA FCRL6 Fc receptor-like 6 343413 ENSG00000181036
12  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
13  ENSG00000156738 NA MS4A1 membrane-spanning 4-domains, subfamily A, member 1 931 ENSG00000156738
14  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
15  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
16  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
17  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
18  ENSG00000110848 NA CD69 CD69 molecule 969 ENSG00000110848
19  ENSG00000013725 NA CD6 CD6 molecule 923 ENSG00000013725
20  ENSG00000148053 NA NTRK2 neurotrophic tyrosine kinase, receptor, type 2 4915 ENSG00000148053
21  ENSG00000160791 NA CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 ENSG00000160791


Database:cellular component       Name:plasma membrane       ID:GO:0005886
C=4289; O=55; E=22.13; R=2.48; rawP=1.34e-13; adjP=3.06e-12
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000131471 NA AOC3 amine oxidase, copper containing 3 (vascular adhesion protein 1) 8639 ENSG00000131471
2  ENSG00000198286 NA CARD11 caspase recruitment domain family, member 11 84433 ENSG00000198286
3  ENSG00000181847 NA TIGIT T cell immunoreceptor with Ig and ITIM domains 201633 ENSG00000181847
4  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
5  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
6  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
7  ENSG00000172215 NA CXCR6 chemokine (C-X-C motif) receptor 6 10663 ENSG00000172215
8  ENSG00000117600 NA LPPR4 lipid phosphate phosphatase-related protein type 4 9890 ENSG00000117600
9  ENSG00000173762 NA CD7 CD7 molecule 924 ENSG00000173762
10  ENSG00000100453 NA GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 3002 ENSG00000100453
11  ENSG00000213903 NA LTB4R leukotriene B4 receptor 1241 ENSG00000213903
12  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
13  ENSG00000111796 NA KLRB1 killer cell lectin-like receptor subfamily B, member 1 3820 ENSG00000111796
14  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
15  ENSG00000128340 NA RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 5880 ENSG00000128340
16  ENSG00000153283 NA CD96 CD96 molecule 10225 ENSG00000153283
17  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
18  ENSG00000013725 NA CD6 CD6 molecule 923 ENSG00000013725
19  ENSG00000142583 NA SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 6518 ENSG00000142583
20  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286
21  ENSG00000213402 NA PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein 5790 ENSG00000213402
22  ENSG00000174946 NA GPR171 G protein-coupled receptor 171 29909 ENSG00000174946
23  ENSG00000180644 NA PRF1 perforin 1 (pore forming protein) 5551 ENSG00000180644
24  ENSG00000237541 NA HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3118 ENSG00000237541
25  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
26  ENSG00000139626 NA ITGB7 integrin, beta 7 3695 ENSG00000139626
27  ENSG00000117091 NA CD48 CD48 molecule 962 ENSG00000117091
28  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
29  ENSG00000145649 NA GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 3001 ENSG00000145649
30  ENSG00000182866 NA LCK lymphocyte-specific protein tyrosine kinase 3932 ENSG00000182866
31  ENSG00000147168 NA IL2RG interleukin 2 receptor, gamma 3561 ENSG00000147168
32  ENSG00000105122 NA RASAL3 RAS protein activator like 3 64926 ENSG00000105122
33  ENSG00000134242 NA PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 26191 ENSG00000134242
34  ENSG00000100385 NA IL2RB interleukin 2 receptor, beta 3560 ENSG00000100385
35  ENSG00000181036 NA FCRL6 Fc receptor-like 6 343413 ENSG00000181036
36  ENSG00000142765 NA SYTL1 synaptotagmin-like 1 84958 ENSG00000142765
37  ENSG00000168421 NA RHOH ras homolog family member H 399 ENSG00000168421
38  ENSG00000141293 NA SKAP1 src kinase associated phosphoprotein 1 8631 ENSG00000141293
39  ENSG00000166086 NA JAM3 junctional adhesion molecule 3 83700 ENSG00000166086
40  ENSG00000156738 NA MS4A1 membrane-spanning 4-domains, subfamily A, member 1 931 ENSG00000156738
41  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
42  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
43  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
44  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
45  ENSG00000115085 NA ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 ENSG00000115085
46  ENSG00000110848 NA CD69 CD69 molecule 969 ENSG00000110848
47  ENSG00000232629 NA HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 3120 ENSG00000232629
48  ENSG00000105374 NA NKG7 natural killer cell group 7 sequence 4818 ENSG00000105374
49  ENSG00000143851 NA PTPN7 protein tyrosine phosphatase, non-receptor type 7 5778 ENSG00000143851
50  ENSG00000186854 NA TRABD2A TraB domain containing 2A 129293 ENSG00000186854
51  ENSG00000162739 NA SLAMF6 SLAM family member 6 114836 ENSG00000162739
52  ENSG00000138964 NA PARVG parvin, gamma 64098 ENSG00000138964
53  ENSG00000148053 NA NTRK2 neurotrophic tyrosine kinase, receptor, type 2 4915 ENSG00000148053
54  ENSG00000023892 NA DEF6 differentially expressed in FDCP 6 homolog (mouse) 50619 ENSG00000023892
55  ENSG00000160791 NA CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 ENSG00000160791


Database:cellular component       Name:cell periphery       ID:GO:0071944
C=4377; O=55; E=22.59; R=2.44; rawP=3.30e-13; adjP=6.27e-12
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000131471 NA AOC3 amine oxidase, copper containing 3 (vascular adhesion protein 1) 8639 ENSG00000131471
2  ENSG00000198286 NA CARD11 caspase recruitment domain family, member 11 84433 ENSG00000198286
3  ENSG00000181847 NA TIGIT T cell immunoreceptor with Ig and ITIM domains 201633 ENSG00000181847
4  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
5  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
6  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
7  ENSG00000172215 NA CXCR6 chemokine (C-X-C motif) receptor 6 10663 ENSG00000172215
8  ENSG00000117600 NA LPPR4 lipid phosphate phosphatase-related protein type 4 9890 ENSG00000117600
9  ENSG00000173762 NA CD7 CD7 molecule 924 ENSG00000173762
10  ENSG00000100453 NA GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 3002 ENSG00000100453
11  ENSG00000213903 NA LTB4R leukotriene B4 receptor 1241 ENSG00000213903
12  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
13  ENSG00000111796 NA KLRB1 killer cell lectin-like receptor subfamily B, member 1 3820 ENSG00000111796
14  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
15  ENSG00000128340 NA RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 5880 ENSG00000128340
16  ENSG00000153283 NA CD96 CD96 molecule 10225 ENSG00000153283
17  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
18  ENSG00000013725 NA CD6 CD6 molecule 923 ENSG00000013725
19  ENSG00000142583 NA SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 6518 ENSG00000142583
20  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286
21  ENSG00000213402 NA PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein 5790 ENSG00000213402
22  ENSG00000174946 NA GPR171 G protein-coupled receptor 171 29909 ENSG00000174946
23  ENSG00000180644 NA PRF1 perforin 1 (pore forming protein) 5551 ENSG00000180644
24  ENSG00000237541 NA HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3118 ENSG00000237541
25  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
26  ENSG00000139626 NA ITGB7 integrin, beta 7 3695 ENSG00000139626
27  ENSG00000117091 NA CD48 CD48 molecule 962 ENSG00000117091
28  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
29  ENSG00000145649 NA GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 3001 ENSG00000145649
30  ENSG00000182866 NA LCK lymphocyte-specific protein tyrosine kinase 3932 ENSG00000182866
31  ENSG00000147168 NA IL2RG interleukin 2 receptor, gamma 3561 ENSG00000147168
32  ENSG00000105122 NA RASAL3 RAS protein activator like 3 64926 ENSG00000105122
33  ENSG00000134242 NA PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 26191 ENSG00000134242
34  ENSG00000100385 NA IL2RB interleukin 2 receptor, beta 3560 ENSG00000100385
35  ENSG00000181036 NA FCRL6 Fc receptor-like 6 343413 ENSG00000181036
36  ENSG00000142765 NA SYTL1 synaptotagmin-like 1 84958 ENSG00000142765
37  ENSG00000168421 NA RHOH ras homolog family member H 399 ENSG00000168421
38  ENSG00000141293 NA SKAP1 src kinase associated phosphoprotein 1 8631 ENSG00000141293
39  ENSG00000166086 NA JAM3 junctional adhesion molecule 3 83700 ENSG00000166086
40  ENSG00000156738 NA MS4A1 membrane-spanning 4-domains, subfamily A, member 1 931 ENSG00000156738
41  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
42  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
43  ENSG00000121966 NA CXCR4 chemokine (C-X-C motif) receptor 4 7852 ENSG00000121966
44  ENSG00000168685 NA IL7R interleukin 7 receptor 3575 ENSG00000168685
45  ENSG00000115085 NA ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 ENSG00000115085
46  ENSG00000110848 NA CD69 CD69 molecule 969 ENSG00000110848
47  ENSG00000232629 NA HLA-DQB2 major histocompatibility complex, class II, DQ beta 2 3120 ENSG00000232629
48  ENSG00000105374 NA NKG7 natural killer cell group 7 sequence 4818 ENSG00000105374
49  ENSG00000143851 NA PTPN7 protein tyrosine phosphatase, non-receptor type 7 5778 ENSG00000143851
50  ENSG00000186854 NA TRABD2A TraB domain containing 2A 129293 ENSG00000186854
51  ENSG00000162739 NA SLAMF6 SLAM family member 6 114836 ENSG00000162739
52  ENSG00000138964 NA PARVG parvin, gamma 64098 ENSG00000138964
53  ENSG00000148053 NA NTRK2 neurotrophic tyrosine kinase, receptor, type 2 4915 ENSG00000148053
54  ENSG00000023892 NA DEF6 differentially expressed in FDCP 6 homolog (mouse) 50619 ENSG00000023892
55  ENSG00000160791 NA CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 ENSG00000160791


Database:cellular component       Name:immunological synapse       ID:GO:0001772
C=22; O=7; E=0.11; R=61.66; rawP=1.22e-11; adjP=1.99e-10
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
2  ENSG00000145649 NA GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 3001 ENSG00000145649
3  ENSG00000168421 NA RHOH ras homolog family member H 399 ENSG00000168421
4  ENSG00000182866 NA LCK lymphocyte-specific protein tyrosine kinase 3932 ENSG00000182866
5  ENSG00000100453 NA GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 3002 ENSG00000100453
6  ENSG00000115085 NA ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 7535 ENSG00000115085
7  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851


Database:cellular component       Name:intrinsic to plasma membrane       ID:GO:0031226
C=1264; O=26; E=6.52; R=3.99; rawP=5.35e-10; adjP=7.62e-09
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000237541 NA HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3118 ENSG00000237541
2  ENSG00000139626 NA ITGB7 integrin, beta 7 3695 ENSG00000139626
3  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
4  ENSG00000117091 NA CD48 CD48 molecule 962 ENSG00000117091
5  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
6  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
7  ENSG00000147168 NA IL2RG interleukin 2 receptor, gamma 3561 ENSG00000147168
8  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
9  ENSG00000105122 NA RASAL3 RAS protein activator like 3 64926 ENSG00000105122
10  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
11  ENSG00000100385 NA IL2RB interleukin 2 receptor, beta 3560 ENSG00000100385
12  ENSG00000172215 NA CXCR6 chemokine (C-X-C motif) receptor 6 10663 ENSG00000172215
13  ENSG00000117600 NA LPPR4 lipid phosphate phosphatase-related protein type 4 9890 ENSG00000117600
14  ENSG00000213903 NA LTB4R leukotriene B4 receptor 1241 ENSG00000213903
15  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
16  ENSG00000156738 NA MS4A1 membrane-spanning 4-domains, subfamily A, member 1 931 ENSG00000156738
17  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
18  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
19  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
20  ENSG00000153283 NA CD96 CD96 molecule 10225 ENSG00000153283
21  ENSG00000110848 NA CD69 CD69 molecule 969 ENSG00000110848
22  ENSG00000013725 NA CD6 CD6 molecule 923 ENSG00000013725
23  ENSG00000105374 NA NKG7 natural killer cell group 7 sequence 4818 ENSG00000105374
24  ENSG00000186854 NA TRABD2A TraB domain containing 2A 129293 ENSG00000186854
25  ENSG00000148053 NA NTRK2 neurotrophic tyrosine kinase, receptor, type 2 4915 ENSG00000148053
26  ENSG00000160791 NA CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 ENSG00000160791


Database:cellular component       Name:alpha-beta T cell receptor complex       ID:GO:0042105
C=4; O=4; E=0.02; R=193.78; rawP=6.62e-10; adjP=8.39e-09
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000167286 NA CD3D CD3d molecule, delta (CD3-TCR complex) 915 ENSG00000167286
2  ENSG00000198821 NA CD247 CD247 molecule 919 ENSG00000198821
3  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
4  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654


Database:cellular component       Name:integral to plasma membrane       ID:GO:0005887
C=1220; O=25; E=6.30; R=3.97; rawP=1.37e-09; adjP=1.56e-08
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000237541 NA HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 3118 ENSG00000237541
2  ENSG00000139626 NA ITGB7 integrin, beta 7 3695 ENSG00000139626
3  ENSG00000005844 NA ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 3683 ENSG00000005844
4  ENSG00000117091 NA CD48 CD48 molecule 962 ENSG00000117091
5  ENSG00000163599 NA CTLA4 cytotoxic T-lymphocyte-associated protein 4 1493 ENSG00000163599
6  ENSG00000198851 NA CD3E CD3e molecule, epsilon (CD3-TCR complex) 916 ENSG00000198851
7  ENSG00000147168 NA IL2RG interleukin 2 receptor, gamma 3561 ENSG00000147168
8  ENSG00000160654 NA CD3G CD3g molecule, gamma (CD3-TCR complex) 917 ENSG00000160654
9  ENSG00000172116 NA CD8B CD8b molecule 926 ENSG00000172116
10  ENSG00000100385 NA IL2RB interleukin 2 receptor, beta 3560 ENSG00000100385
11  ENSG00000172215 NA CXCR6 chemokine (C-X-C motif) receptor 6 10663 ENSG00000172215
12  ENSG00000117600 NA LPPR4 lipid phosphate phosphatase-related protein type 4 9890 ENSG00000117600
13  ENSG00000213903 NA LTB4R leukotriene B4 receptor 1241 ENSG00000213903
14  ENSG00000116824 NA CD2 CD2 molecule 914 ENSG00000116824
15  ENSG00000156738 NA MS4A1 membrane-spanning 4-domains, subfamily A, member 1 931 ENSG00000156738
16  ENSG00000110448 NA CD5 CD5 molecule 921 ENSG00000110448
17  ENSG00000234745 NA HLA-B major histocompatibility complex, class I, B 3106 ENSG00000234745
18  ENSG00000153563 NA CD8A CD8a molecule 925 ENSG00000153563
19  ENSG00000153283 NA CD96 CD96 molecule 10225 ENSG00000153283
20  ENSG00000110848 NA CD69 CD69 molecule 969 ENSG00000110848
21  ENSG00000013725 NA CD6 CD6 molecule 923 ENSG00000013725
22  ENSG00000105374 NA NKG7 natural killer cell group 7 sequence 4818 ENSG00000105374
23  ENSG00000186854 NA TRABD2A TraB domain containing 2A 129293 ENSG00000186854
24  ENSG00000148053 NA NTRK2 neurotrophic tyrosine kinase, receptor, type 2 4915 ENSG00000148053
25  ENSG00000160791 NA CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 1234 ENSG00000160791




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).